It is also classified as a heterocycle derived from cyclopentane by replacing two methylene bridges (-CH2- units) with a disulfide group.
The parent molecule is unimportant but substituted derivatives, especially lipoic acid and its derivatives, are often essential for life.
[2] In general, 1,3-dithiols are superior reductants relative to monothiols.
[5] The 4-dimethylamino derivative nereistoxin was the inspiration for insecticides that act by blocking the nicotinic acetylcholine receptor.
[6] Several alkyl-substituted 1,2-dithiolanes occur in the scent glands of skunks and related mammals.