One Independence Center is a high-rise office building located in Uptown Charlotte, North Carolina.

[9] The developers Faison firm and Williams Realty of Tulsa, Oklahoma announced in October 1981 the specifics of the building.

[12] In October 1983 Smith Barney Harris Upham & Co. Inc., a stock brokerage, left NCNB Plaza.

Wheat, First Securities Inc., a stock brokerage moved from a 5,000 square feet (465 m2) space at Northwestern building.

[14] In November 1983 law firm Fleming, Robinson, Bradshaw & Hinson signed a lease for 20,000 square feet (1,858 m2) on the top two floors.

The building was 92% occupied at the time of the sale with Bank of America Corp. and the Robinson, Bradshaw & Hinson law firm as the anchor tenants.

At the time of signing the renewal they had 125 local employees and were the second largest law firm in Charlotte after Moore & Van Allen.

[22] In October 2011 Northeastern University opened its Charlotte with 14,000 square feet (1,301 m2) in the building for offices and classrooms.

Accounting firm CliftonLarsonAllen vacated the tenth floor earlier in 2015 which left 119,296 square feet (11,083 m2) of continuous space available.

[28][29] The renovations included adding a collobration area to the atrium, new art work in the lobby, and updated hallways and restrooms.

[29] The building was 80% leased as of August 2020,[29] its tenants included Bank of America, Robinson Bradshaw, Levvel, Northeastern University, and Sunlight Financial and Spaces.

[32] In May 2022 Robinson Bradshaw announced they will vacate their space in the building in 2024 when 600 South Tryon is complete to become the anchor tenant occupying 102,000 square feet (9,476 m2).

[33][34] In July 2022 Stays by Walker, a short term rental agency, announced they will be leasing 3,000 square feet (279 m2) in the building.

Kay Walker, CEO of Stays Walker, stated this about the space “The proximity to so many of Charlotte's major corporate players will be a huge asset to our company, and our team members will enjoy the property's newly renovated common spaces and top-of-the-line amenities.

The quality of the improvements of the office space was very high-end and consistent with the high-quality offerings we make to our clients.”[35] In August 2022 UK based The Bank of London announced it will be leasing 40,000 square feet (3,716 m2) in the building to house the 350 jobs they're creating in Charlotte.

These include Barley and Burger, serving gourmet burgers; Curry Junction, a concept by the owners of Curry Gate, an Indian and Nepalese restaurant; Rolled AF, is a Mexican restaurant that is a joint operation by the owners of Nacho Average Truck and 22 Street Kitchen.

[41] The recently completed $25 million renovation which included Monarch Market are contributing to an increase in occupancy.

In February 2024 Crescent Communities announced it had signed six leases amounting to 68,600 square feet (6,373 m2) space.