The 101st Independent Brigade of the Territorial Defense Forces (Ukrainian: 101-ша окрема бригада територіальної оборони) is a military formation of the Territorial Defense Forces of Ukraine in Zakarpattia Oblast.

It is part of Operational Command West.

From 19 to 28 September 2019 Brigade held large scale exercise for over 2,000 reservists.

[2] Units of the Brigade served in defence of Popasna in April.

Then defended Hirske, Serhiivka, Volodymyrivka[3] and Spirne.