On July 12, the regiment was mustered into the United States service with under Major Charles Devens Jr.

On 22 August 1917 the company was mobilized as an element of the 101st Supply Train, a part of the 26th Division, at Camp Bartlett, Massachusetts.

In France the Company served in all of campaigns of the Yankee Division The unit was demobilized 29 April 1919 at Camp Devens, Massachusetts.

The unit was reorganized and redesignated 26 May 1936 as Company C, 101st Quartermaster Regiment, an element of the 26th Division.

The company was mobilized in January 1941 for one year of training with the Yankee Division.

The year of training ended in December 1941 but the company's service continued after the Japanese attack on Pearl Harbor brought the United States into the Second World War.

The unit was reorganized and redesignated 1 March 1988 as Company B, 726th Support Battalion.