In June 1898 The Hudson Light Guards was mobilized for the war with Spain and served at Gunville, South Carolina.

Infantry was mobilized for service on the Mexican Border at El Paso, Texas.

They received standard infantry training so that they could defend themselves, but there are very few documented instances of any pioneer troops unslinging their rifles.

The year of training ended in December 1941 but the company's service continued after the Japanese attack on Pearl Harbor brought the United States into the Second World War.

In September 2005, Company mobilized as an element of JTF Yankee for rescue and security operations in New Orleans following Hurricane Katrina.

In August 2010, Company D 1-181 IN deployed for one year of service with the International Security Force in Afghanistan in support of Operation Enduring Freedom.

The company coordinated force protection at Camp Phoenix and conducted security operations in Ghazni, Zabul and Farrah (detachment from Arizona National Guard) Provinces.