1921 Detroit Tigers (NFL) season

The 1921 Detroit Tigers season was their second completed in the young American Professional Football Association (APFA), an organization soon to be renamed the National Football League.

The team failed to improve on their previous output of 2–3–3 (when the team was still known as the Heralds), winning only one game.

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Newspaper ad promoting the 1921 season opener of the Tigers in Rock Island, Illinois, where they met the Independents.