Paul B. Johnson Sr. Democratic Thomas L. Bailey Democratic The 1943 Mississippi gubernatorial election took place on November 2, 1943 to elect the Governor of Mississippi.

Incumbent Democrat Paul B. Johnson Sr. was term-limited, and could not run for reelection to a second term (he died less than two months after the election was held).

As was common at the time, the Democratic candidate ran unopposed in the general election so therefore the Democratic primary was the real contest, and winning the primary was considered tantamount to election.

The runoff election was won by former state representative Thomas L. Bailey, who defeated former Governor Martin S. Conner.

In the general election, Bailey ran unopposed.