The 1980–81 Creighton Bluejays men's basketball team represented Creighton University during the 1980–81 NCAA Division I men's basketball season.
The Bluejays, led by head coach Tom Apke, played their home games at the Omaha Civic Auditorium.
The Jays finished with a 21–9 record (11–5 MVC), and won the Missouri Valley Conference tournament[2] to earn an automatic bid to the 1981 NCAA tournament.
8 seed in the Mideast region, the Jays fell to No.
9 seed Saint Joseph's in the opening round.