The 1999–2000 Creighton Bluejays men's basketball team represented Creighton University during the 1999–2000 NCAA Division I men's basketball season.

The Bluejays, led by head coach Dana Altman, played their home games at the Omaha Civic Auditorium.

The Jays finished with a 23-10 record, and won the Missouri Valley Conference tournament to earn an automatic bid to the 2001 NCAA tournament.

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