In second place was previous two-time Tour winner Laurent Fignon (Super U–Raleigh–Fiat), ahead of Pedro Delgado (Reynolds), the defending champion.
Delgado launched several attacks in the mountain stages to eventually finish third, while LeMond rode defensively to preserve his chances.
In the closest Tour in history, LeMond was trailing Fignon by fifty seconds at the start of the final stage, an individual time trial into Paris.
Not invited was the Teka team, which failed to accumulate enough points in the World Rankings after Reimund Dietzen had to leave the 1989 Vuelta a España following a career-ending crash.
[15] In 1989 however, a victory at Milan–San Remo and more importantly, the three-week Grand Tour in Italy, the Giro d'Italia, had propelled Fignon back into the spotlight.
Kelly's PDM squad also had two talented Dutch riders in their ranks with hopes of a high finish: Steven Rooks, who had been second the year before, and Gert-Jan Theunisse.
Since PDM had elected not to start either the Giro d'Italia or the Vuelta a España earlier in the season, the team hoped that their riders, without an additional three-week race in their legs, would be fresher than their rivals.
[17] Other favourites included Erik Breukink (Panasonic–Isostar), Andrew Hampsten (7-Eleven), Steve Bauer (Helvetia–La Suisse), Fabio Parra (Kelme) and Robert Millar (Z–Peugeot).
On the first stage, Acácio da Silva (Carrera Jeans–Vagabond) won from a breakaway group to become the first Portuguese rider to wear the yellow jersey.
[36] The third stage, finishing at the racing circuit of Spa-Francorchamps, was won by Raúl Alcalá (PDM–Ultima–Concorde), who got the best of a five-man breakaway group up the climb to the line.
[41][e] Fignon and his team manager Cyrille Guimard felt that the tribars were not within the regulations, since they only allowed three support points for the rider on the bike.
[43][f] Delgado rode a strong time trial, supported by favourable weather conditions as he competed in the dry, while later starters had to get through the rain.
On stage 9 from Pau to Cauterets, future five-time Tour winner Miguel Induráin (Reynolds) attacked on the bottom of the Col d'Aubisque and led the race for the rest of the day.
[50] It was on this stage that Fignon started to complain about LeMond riding too defensively for strategic reasons, accusing him of not putting any work into counterattacks.
[52] Former race winner Stephen Roche hit his already injured knee on his handlebars on the descent of the Col de Marie-Blanque, reaching the finish under extreme pain many minutes behind the other favourites.
Behind them, Fignon suffered a weak moment on the climb and allegedly held on to a photographer riding on a motorcycle, without the race directors handing out any punishment for the offence.
Fignon attacked LeMond within the final kilometre of the stage, taking twelve seconds on the general classification and with it the yellow jersey.
With just a couple of hundred metres left and the stage win almost certainly in his hands, Dhaenens misjudged his speed going through a corner and crashed, allowing the rest of the field to pass him.
[57][58] Stage 12 was interrupted by an ecologists' protests against a new waste plant, which aided a breakaway by Valerio Tebaldi (Chateau d'Ax) and Giancarlo Perini (Carrera Jeans–Vagabond).
Delgado was handed a ten-second time penalty for illegally accepting food outside the feed zone, while pre-race favourite Breukink retired from the race about 30 km (19 mi) from the finish.
The day's breakaway, which included Luis Herrera (Café de Colombia), a pre-race contender who had so far disappointed, was caught within the last 1.5 km (0.93 mi) of the stage.
Of the true contenders for the overall victory, Delgado set the fastest times at all the check points, but slowed on the last climb to eventually finish the stage fourth, 48 seconds down on Rooks.
He passed the summit of the climb 15 seconds clear of his pursuers and in the valley behind, a group containing Alcalá and Kelly caught up to the three chasers.
Already by the second climb of the day, the Col de Porte, the top-four riders on the general classification, Fignon, LeMond, Delgado and Theunisse, joined by seventh-placed Lejarreta, had pulled clear.
Going into the town of Chambéry, site of the World Championships one month later, Lejarreta misjudged a roundabout and crashed, taking all riders with him but Delgado, who waited for the others to remount and join him.
The five riders settled the stage win in a sprint finish, with LeMond taking the honours, although the difference between him and Fignon in the overall standings remained at 50 seconds.
[69] With the final-stage time trial to Paris looming ahead, the field took a steady pace on stage 20 from Aix-les-Bains to L'Isle d'Abeau.
[70] After stage 19, Fignon had developed saddle sores, which gave him pain and made it impossible to sleep the night before the time trial.
[101] Commemorating the bicentennial anniversary of the French Revolution, a cash prize of 17,890 francs was given out to the first rider passing the 1,789th kilometre of the race at Martres-Tolosane, on stage 11 between Luchon and Blagnac.
[114] There was also a Souvenir in honour of five-time Tour winner Jacques Anquetil, who had died two years before, given to the rider who wore the yellow jersey for the most days.