The Second League of Yugoslavia's 1991/1992 season was the last in which teams from Bosnia and Herzegovina and Macedonia participated, as well as the last of the Socialist Federal Republic of Yugoslavia in general as the Second League of FR Yugoslavia was established the following season.
In 1992 these republics declared their independence from Yugoslavia.
The clubs from Croatia and Slovenia were already playing their first seasons as separate nations.
FK Teteks, that finished 12 and would eventually have maintained their status, along with eventually relegated FK Balkan Skopje, became members of the 1992–93 First Macedonian Football League in next season.
The rest of the clubs that would eventually be relegated were all from the territory of Bosnia and Herzegovina, and all left the Yugoslav league system.