The 1991 Miller Genuine Draft 500 was the 16th stock car race of the 1991 NASCAR Winston Cup Series season and the 19th iteration of the event.

The race was held on Sunday, July 21, 1991, in Long Pond, Pennsylvania, at Pocono Raceway, a 2.5 miles (4.0 km) triangular permanent course.

The race was held at Pocono International Raceway, which is a three-turn superspeedway located in Long Pond, Pennsylvania.

During regular non-race weekends, multiple clubs can use the track by running on different infield sections.

Alan Kulwicki, driving for his own AK Racing team, would win the pole, setting a time of 55.737 and an average speed of 161.473 miles per hour (259.866 km/h) in the first round.