1991 NCAA Division I men's basketball tournament

Duke, coached by Mike Krzyzewski, won a rematch of the previous year's national final matchup against undefeated UNLV 79–77 in the semifinal,[1] then won the national title with a 72–65 victory in the final game over Kansas, coached by Roy Williams.

Kansas made its second trip to the national championship game in four seasons, the prior appearance being 1988 when they defeated Oklahoma.

Five conference champions made their first NCAA tournament appearances: Coastal Carolina (Big South), Georgia State (TAAC), Green Bay (Mid-Continent), Saint Francis (PA) (NEC), and Saint Peter's (MAAC).

During the weekend of the second round, the national telecast began at noon, with the regional windows (three on Saturday, two on Sunday) following.

As of 2011, the regional broadcasts have been replaced by simulcast feeds on non-broadcast networks owned by Turner Sports.