Head coach Mike Shanahan announced that third-round 1998 draft pick Brian Griese, son of Miami Dolphins quarterback Bob Griese, would take the reins of the offense, passing over veteran and credible back-up quarterback Bubby Brister.
On August 7, before a crowd of 73,811 spectators at Stadium Australia in Sydney, the Broncos defeated the San Diego Chargers 20–17.
The 11-21 mark was matched by the Tampa Bay Buccaneers and Oakland Raiders four years later, one season removed from Super Bowl XXXVII.
Denver had ridden the third-easiest schedule (in a 30-team league) to a Lombardi Trophy in 1998, only to fall apart the next season under the weight of John Elway's retirement, Terrell Davis'[s] Week 4 injury, and – oh, by the way – the toughest schedule in the league.This was the largest single-season change in Football Outsiders' rankings until the 2011 St. Louis Rams.
Week 4 saw star running back Terrell Davis, who was last year's league MVP, hurt his knee and was placed on injured reserve for the remainder of the season.