Marino suffered an injury on October 17 against the New England Patriots, with Damon Huard taking over at quarterback.
1 seed Jacksonville Jaguars, losing 62–7, the most lopsided playoff loss in the Super Bowl era.
The Dolphins opened the season on the road against the defending Super Bowl champion Denver Broncos.
In the 4th quarter, Griese fumbled the ball, with Jason Taylor recovering it and running it into the end zone for a touchdown.
The Dolphins were trailing 31–22 in the 4th quarter before staging a furious comeback with just under 3:30 left to play, scoring 12 unanswered points in the span of nearly 3 minutes.
With 1:54 left, Miami's defense forced Peyton Manning to run out the end zone, resulting in a safety.
On the ensuing drive, Dan Marino led the offense down the field, capping it off with a 2-yard pass to Oronde Gadsden for the game-winning score.
On Marino's second pass attempt, he was hit by Lawyer Milloy, with Andy Katzenmoyer intercepting the ball and returning it 57 yards for a touchdown.
[2] Marino was replaced by Damon Huard, whose first pass was intercepted by Ty Law and returned 27 yards for a touchdown.
Despite the rocky start, Huard would lead the Dolphins to a 31–30 comeback victory, throwing a 5-yard touchdown pass to fullback Stanley Pritchett with 23 seconds left in the game for the game-winning score.
The game's only offensive score came in the 4th, with Troy Aikman throwing a 65-yard touchdown pass to Rocket Ismail.
The Dolphins trailed 24–10 at halftime, but tied the game twice in the 4th quarter, including a 32-yard field goal from Olindo Mare with 0:36 left in regulation.
However, Indianapolis kicker Mike Vanderjagt made a 53-yard field goal as time expired to give the Colts a 37–34 victory.
The Jets scored 22 unanswered points in the 4th quarter, including a 67-yard interception return by Omar Stoutmire.
Although Seattle jumped out to a 17–10 lead in the 3rd quarter, the Dolphins would rally back behind quarterback Dan Marino, who threw for 196 yards and a touchdown, leading his team to their first road playoff win since 1972 in what ultimately proved to be the final game played at The Kingdome (the Seahawks moved into Husky Stadium for the 2000 season) and the final win of Marino's career.
The Jacksonville Jaguars shredded their in-state rivals the Dolphins with 520 total offensive yards in what became Miami quarterback Dan Marino's last game in the NFL and the most lopsided postseason contest since the Chicago Bears defeated the Redskins 73–0 in the 1940 NFL Championship Game.