[2][3] 2-Ethoxyethyl acetate has been used to dissolve polyester and short oil alkyd resins.

[5] It is also a solvent for nitro-cellulose and is being used for the same applications as ethyl glycol[4][6] In automobile lacquers it has been used to reduce evaporation and to impart a high gloss.

These two compounds are the likely active metabolites, which are thought to be involved in some of the toxic effects.

An extra pathway in these animals involves microsomal P450 mixed function oxidases, with deethylation producing acetaldehyde and ethylene glycol.

[9] 2-Ethoxyethyl acetate can cause a slight skin and eye irritation after exposure.