2-Hydroxy-N-methyltryptamine (2-HO-NMT) is a tryptamine and is the 2-hydroxy analog of N-methyltryptamine (NMT).

It is briefly mentioned in Alexander Shulgin's book TiHKAL (Tryptamines I Have Known and Loved) under the DMT entry and is stated to be found in Desmanthus illinoensis.

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