The 2000 Nabisco Championship was a women's professional golf tournament, held March 23–26 at Mission Hills Country Club in Rancho Mirage, California.

This was the 29th edition of the Kraft Nabisco Championship, and the eighteenth as a major championship.

Karrie Webb won the first of her two titles in this event, ten strokes ahead of Dottie Pepper, the defending champion.

[3] Webb held an eight-stroke lead after 54 holes,[4] and shot a final round 70 for a comfortable victory.

[2][3] Sunday, March 26, 2000 (a) - denotes amateur