The 2005–06 Slovak First Football League (known as the Slovak Corgoň Liga for sponsorship reasons) was the 13th season of first-tier football league in Slovakia, since its establishment in 1993.

[1] FC Artmedia Bratislava were the defending champions.

A total of 10 teams was contested in the league, including 9 sides from the 2004–05 season and one promoted from the 2.

Relegation for FC Rimavská Sobota to the 2005–06 2.

The one relegated team were replaced by FC Nitra.