This fate would again be suffered by the 2012 Detroit Tigers, being swept by the San Francisco Giants in the World Series after sweeping the New York Yankees in the ALCS.

Over the course of 29 days in September through the middle of October, the Rockies won 21 games and lost just once, including sweeps of the Philadelphia Phillies in the NLDS and the division rival Arizona Diamondbacks in the NLCS.

Per the 2006 Collective Bargaining Agreement,[4] the Red Sox had home-field advantage in the World Series following the American League's 5–4 win in the 2007 All-Star Game.

Rookie Dustin Pedroia led off the Sox' first inning with a home run over the Green Monster in Fenway Park off of Jeff Francis.

Pedroia's homer was only the second lead-off home run to start a World Series (the only other one was hit by Baltimore's Don Buford in 1969).

After Mike Lowell flew out, Jason Varitek singled before J. D. Drew doubled to score Ramirez and make it 3-0 Red Sox.

The ceremonial first pitch was thrown by Andrew Madden, a 13-year-old heart transplant recipient, accompanied by Boston Red Sox Hall of Fame member Dwight Evans.

[16] After the debacle of Game 1, Colorado appeared to return to form, scoring quickly on a groundout by Todd Helton with runners on second and third in the first.

After Matsuzaka walked two straight in the sixth with one out, reliever Javier López allowed back-to-back RBI singles to Brad Hawpe and Yorvit Torrealba.

Jason Varitek would tack on Boston's tenth run in the top of the ninth off of LaTroy Hawkins with a sacrifice fly, scoring Mike Lowell who, not generally considered a stolen base threat, had just stolen third base—the first time a Red Sox baserunner stole third base in the World Series since 1975—after hitting a leadoff single and moving to second on a sacrifice bunt.

Rookie Jacoby Ellsbury began the first inning with a double and was advanced by Dustin Pedroia with a groundout, followed by an RBI single from David Ortiz.

In the seventh inning, Lowell hit a home run to give Boston a 3–0 lead and knock starter Aaron Cook out of the game.

The Colorado offense answered when left fielder Brad Hawpe hit a home run off of a Manny Delcarmen fastball, bringing the Rockies within two.

Relief pitcher Brian Fuentes gave back that run abruptly, allowing Boston pinch-hitter Bobby Kielty to hit a ball into the left field stands on the first pitch of the inning, extending the Red Sox lead to 4–1.

In the bottom of the inning Boston pitcher Hideki Okajima allowed a one-out single to Todd Helton followed by a Garrett Atkins two-run home run, bringing the Rockies within one.

There was controversy in the top of the eighth when Fox's broadcast announced that Alex Rodriguez would be opting out of his contract with the Yankees to become a free agent.

[17] Commissioner Bud Selig made it clear during the World Series that an embargo had been placed on all Major League Baseball stories until the sport's top event had come to an end.

[71] The Red Sox victory parade, yet again in duck boats and called a "Rolling Rally" as in 2004, was on October 30, 2007 with closer Jonathan Papelbon doing his infamous "Irish Jig" while local punk band the Dropkick Murphys played their hit "I'm Shipping Up to Boston".

The World Series was televised by Fox in the United States, with Joe Buck and Tim McCarver as booth announcers.

Rogers Sportsnet (RSN) in Canada used the MLB International feed with Dave O'Brien and Rick Sutcliffe as booth announcers.

Pitching coach John Farrell served as the skipper of the 2013 Red Sox, featuring 2007 holdovers Clay Buchholz (DNP), Jacoby Ellsbury, Jon Lester, David Ortiz, and Dustin Pedroia.

The 2011 season saw the Red Sox hold a nine-game lead in the wild card heading to September, only to lose 13 of their final 20 games to miss the playoffs.

The Rockies never finished higher than third place in the NL West between 2010 and 2017, though in the latter season, they returned to postseason play as a second wild-card team.

The following season, the Rockies made consecutive postseason appearances for the first time in team history, winning the Wild Card Game against the Chicago Cubs, but losing in the NLDS to the Milwaukee Brewers 3–0.

After managing the Rockies, Hurdle was hired by the Pittsburgh Pirates in 2011, and in 2013, ended a major North American professional sports record 20-year drought without a winning season.

The Pirates proceeded to make the postseason three consecutive years under Hurdle, winning the 2013 National League Wild Card Game during that span.