The knockout phase of the 2010–11 UEFA Champions League began on 15 February and concluded on 28 May 2011 with the final at Wembley Stadium in London, England.
The team that had the higher aggregate score over the two legs progressed to the next round.
If away goals were also equal, then 30 minutes of extra time were played, divided into two 15-minute halves.
If no goals were scored during extra time, the tie was decided by a penalty shoot-out.
If scores were level at the end of normal time in the final, extra time was played, followed by penalties if scores remained tied.
For this draw, there were no seedings, and teams from the same group or the same association could be drawn with each other.
The 2011 UEFA Champions League Final was played on 28 May 2011 at Wembley Stadium in London, England.