The fixtures were announced on 29 July 2010; the season began on 7 August 2010 and ended on 28 May 2011.
[1] Neftchi Baku were the eventual champions, winning their first Azerbaijani championship since 2005.
The first stage consisted of a regular home-and-away round-robin schedule for a total of 22 matches per team.
[2] In contrast to the previous season, each team transferred their full record from the first to the second stage.
[4] Standard Sumgayit and Karvan were relegated to the Azerbaijan First Division after finishing 11th and 12th, respectively, at the end of last season.