The 2010 AFC President's Cup was the sixth edition of the AFC President's Cup, an annual international association football competition between domestic clubs sides run by the Asian Football Confederation (AFC).

The draw for the AFC President's Cup 2010 was held at AFC House on 5 March 1500 hours local time.

The best runners-up team from among the three pools qualify for the semi-finals.

Note on tie-breaking situation: The final stage of the competition will be played in Myanmar from 24 to 26 September.

[5] The semi-final draw was made on 11 July.