The 2010 Armenian Premier League season was the nineteenth since its establishment.

FC Pyunik were the defending champions, having won their twelfth championship last season.

Ararat Yerevan finished in last place last season and were relegated to the Armenian First League.

Taking their place this year is Impuls FC Dilijan, who finished first in the 2009 Armenian First League.

Including matches played on November 14, 2010; Source: ffa.am