[1] A total of 47 teams competed in the 2010 competition which commenced on the weekend ending Sunday 21 March 2010.
As winners of the competition, Sligo Rovers earned spots in both the third qualifying round of the 2011–12 UEFA Europa League and the 2011 Setanta Sports Cup.
The draw for the fourth round took place on 7 June 2010 on Monday Night Soccer.
The draw for the quarter-finals took place on 30 August 2010 on Monday Night Soccer.
[5] The draw for the semi-finals took place on 20 September 2010 on Monday Night Soccer.