The 2010 GP Ouest-France was a one-day road race which took place on 22 August 2010 in Plouay, France.

The race was held over 248.3 kilometres (154.3 mi), which is 12 laps of a circuit.

2010 was the sixth time that the race was a part of the UCI ProTour, but the race can be dated back to 1931 at its present location.

Twenty five teams were invited to the 2010 GP Ouest-France.

Teams from the UCI Pro Tour Teams awarded a wildcard invitation This cycling race article related to French cycling is a stub.