The 2010 Internationaux de Strasbourg was a tennis tournament played on an outdoor clay court.

It was the 24th edition of the Internationaux de Strasbourg, and was part of the International-level tournaments of the 2010 WTA Tour.

It took place at the Centre Sportif de Hautepierre in Strasbourg, France, from 17 May until 22 May 2010.

The following players received wildcards into the main draw: The following players received entry from the qualifying draw: The following player received the lucky loser spot: Maria Sharapova defeated Kristina Barrois, 7–5, 6–1 Alizé Cornet / Vania King defeated Alla Kudryavtseva / Anastasia Rodionova, 3–6, 6–4, [10–7]