The 2010 Tashkent Open was a women's tennis tournament played on outdoor hard courts.

It was the 12th edition of the Tashkent Open, and is part of the WTA International tournaments of the 2010 WTA Tour.

Seventh-seeded Alla Kudryavtseva won the singles title.

Alla Kudryavtseva defeated Elena Vesnina 6–4, 6–4.

Alexandra Panova' / Tatiana Poutchek defeated Alexandra Dulgheru / Magdaléna Rybáriková, 6–3, 6–4 The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received the lucky loser spot: