It started in March and ended in November.
The 9th placed team of Meistriliiga, Kuressaare, and the fourth place team of Esiliiga, Kiviõli Tamme Auto competed in a two-legged relegation play-off for one spot in 2011 Meistriliiga.
Kuressaare won the play-off 4–2 on aggregate and retained their spot in the league.
Each team played every opponent four times, twice at home and twice on the road, for a total of 36 games.
Sander Post was named Meistriliiga Player of the Year.