Red Berets and Mahakama, were relegated to the Nationwide League for the following season, but the former disbanded due to immense pressure from its sponsors to produce good performances.

Sofapaka beat West Kenya Sugar 2–0 in the final to lift the title for the second time their history.

The 2010 CAF Champions League began on February 12, 2010, and finished on November 13, 2010.

Sofapaka qualified for participation in the tournament as 2009 Kenyan Premier League champions.

A.F.C Leopards qualified for participation in the tournament as 2009 FKL Cup champions.