The 2012 season was the Jacksonville Jaguars' 18th in the National Football League (NFL), their first under the ownership of Shahid Khan, and the only season for head coach Mike Mularkey.

The Jaguars entered the season hoping to improve on their 5–11 record from 2011 and return to the playoffs for the first time since 2007, but did not and were eliminated from postseason contention.

The Jaguars finished with a 2–14 record, not only tying the Kansas City Chiefs for the league's worst record of 2012, but it would also be the worst in franchise history until the team went 1–15 in 2020.

The following is a list of notable rookie free agents signed after the 2012 NFL draft: Notes: Front office Head coaches Offensive coaches Special teams coaches Strength and conditioning

Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve Note: Intra-division opponents are in bold text.