Several organizations helped secure the area, search for survivors and aid people who lost their homes.

Primary suspects were Litoral Gas (the natural-gas provider for Rosario) and an employee who carried out maintenance work at the building that day.

[3] Mónica Fein, mayor of Rosario, asked residents to avoid the area because of the risk that more buildings might collapse, and to ease the work of disaster management personnel.

[9] Gas and electricity were immediately disconnected, and the national government sent an Argentine Federal Police task force to the scene.

[18] According to witnesses, one employee fled in a van before the explosion, when he realized the severity of the gas leak, while another remained to try to evacuate people from the endangered area.

[20][21] Prosecutor Graciela Argüelles said that, according to the investigation, Litoral Gas ignored calls for help from García, who was not properly trained to manage such a situation.

[24] As the case expanded beyond his jurisdiction, Curto recused himself from the trial and was replaced by Javier Beltramone,[25] who released García from prison.

[2] García had claimed that he was following instructions received in the days before the explosion, so Bilotta summoned the technical officers of Litoral Gas to clarify that point.

[29] Litoral Gas proposed an out-of-court settlement to the relatives of the victims, offering about 1200 US dollars per square meter of collapsed building, in addition to compensation for loss of life.

The governor of Santa Fe province, Antonio Bonfatti, asked the political parties to end their campaigns to allow mourning for the victims of the explosion.

She was berated by local residents;[39] some were angry because her surprise visit halted work at the site, and others thought her presence was politically motivated.

[41] Weeks before the explosion, several social networking sites had scheduled a country-wide cacerolazo (a pot-banging protest demonstration), known as 8A, against Kirchner for August 8.

[46][47] Pope Francis sent a letter of condolence to Archbishop José Luis Mollaghan of Rosario, and it was read during a mass and procession for Saint Cajetan at Plaza 25 de Mayo.

[52] Musicians Fito Páez,[53] Vicentico, Babasónicos, Las Pelotas, Chaqueño Palavecino, Ciro Pertusi, Lisandro Aristimuño, Pablo Dacal and Coki Debernardi [es] performed concerts in several Argentine cities to raise money for the victims.

[56][57] Rosario's real estate firms prepared a list of houses for rent without charging victims their regular fee.

Engineers began checking the buildings at ground zero, trying to restore the original layout of the street and demolishing unstable structures.