[44] Kris Bryant was tied with Todd Frazier of the Chicago White Sox and Mark Trumbo of the Baltimore Orioles for the Major League Home Run lead with 23 and was fourth with 61 RBIs.

It was announced that the July 12th All-Star game in San Diego would begin with the entire Cubs infield (Bryant, Rizzo, Russell, and Zobrist) as starters.

The Cubs offense, when compared to all major league teams, was among the leaders in on-base percentage (.343), base runners who eventually score (808), RBI's and drawing walks (656).

Infielders Coaches The Cubs began postseason play with starter Jon Lester on the mound facing Johnny Cueto for the Wild Card Game-winning Giants.

Aroldis Chapman appeared for the save in the ninth and gave up a double to Buster Posey, but shut the Giants down as the Cubs took a 1–0 series lead.

In the top of the third, the Giants answered, scoring two runs on back-to-back doubles by Joe Panik and pinch-hitter Gregor Blanco and a sacrifice fly by Brandon Belt.

Reliever Travis Wood ended the Giants' rally and, in the bottom half of the inning, hit a solo home run to put the Cubs up 5–2.

[149] The Cub bullpen of Carl Edwards Jr., Mike Montgomery, and Héctor Rondón shut down the Giants for the remainder of the game with Aroldis Chapman getting the save.

In the ninth, trailing 5–3, Dexter Fowler led off with a walk and Kris Bryant hit a two-run home run off Giants' closer Sergio Romo to tie the game.

Lackey started off slow, allowing a leadoff double to Denard Span and a sacrifice fly by Buster Posey to give the Giants an early 1–0 lead.

Moore cruised through the next three innings, retiring the Cubs in order in the eighth before being lifted for the Giants' bullpen to start the ninth as it appeared a Game 5 was inevitable.

In the top of the eighth, the Dodgers loaded the bases off Cubs relievers Mike Montgomery and Pedro Strop, bringing Aroldis Chapman into the game with no outs.

Chapman struck out the first two batters he faced and appeared to be on the verge of escaping the inning, but Adrián González singled up the middle scoring two runs and tying the game at three.

[159] As the series shifted to Los Angeles, the Cubs looked to break out of their hitting slump and sent Jake Arrieta to the mound, the Dodgers countered with Rich Hill.

Playoff veteran John Lackey took the mound for the Cubs as the Dodgers sent Julio Urías, the youngest pitcher to start a game in postseason history.

In the bottom of the second, the Dodgers had a scoring chance denied as Adrián González was thrown out at the plate by Jason Heyward after an Andrew Toles single.

Pinch hitter Albert Almora, Jr. bunted the runners over and Dexter Fowler followed with an infield singled to score the Cubs' fourth run of the game.

Cub closer Aroldis Chapman pitched the ninth and allowed a run-scoring single by Josh Reddick and a sacrifice fly by Andrew Toles to make the score 8–4.

In the top of the ninth, Chapman walked the second batter, but Yasiel Puig grounded into a game-ending double play as Wrigley Field erupted in celebration.

To begin the historic World Series, the teams sent their number one starters to the mound in Cleveland: Corey Kluber for the Indians and Jon Lester for the Cubs.

However, Miller induced a shallow fly ball by pinch hitter Willson Contreras and struck out Addison Russell and David Ross to end the Cub threat.

Both teams threatened in the seventh but could not score and, following a single by Mike Napoli in the bottom of the eighth, Aroldis Chapman entered to finish the game for the Cubs.

Following a single by Tyler Naquin, a bunt by Tomlin, a walk to Carlos Santana, Hendricks hit Jason Kipnis with a pitch to load the bases in the fifth.

In the bottom of the seventh, the Cubs threatened to tie it with a two-out triple by Jorge Soler, but Javier Báez grounded out to end the inning.

Following an error by Kris Bryant and an intentional walk of Tyler Naquin, Kluber singled home the go-ahead run giving the Indians the 2–1 lead.

[191] Fowler hit a consolation eighth inning solo home run off of reliever Andrew Miller, but that was it as the Cubs lost 7–2 and fell behind in the series three games to one.

Facing elimination and the last game at Wrigley Field for the season, the Cubs sent ace Jon Lester to the mound while the Indians countered with Trevor Bauer.

[196] After giving up a run-scoring single to Pérez and walking Carlos Santana, Travis Wood entered to get the final out and force a game seven in the series.

Hendricks held the Indians scoreless until the third when Coco Crisp doubled, was moved to third on a sacrifice bunt by Roberto Pérez, and scored on a single by Carlos Santana.

Addison Russell hit a shallow fly ball to left field which allowed Bryant to tag and score to put the Cubs up 2–1.