The 2017–18 Missouri State Lady Bears basketball team represented Missouri State University during the 2017–18 NCAA Division I women's basketball season.

The Lady Bears, led by fifth year head coach Kellie Harper, played their home games at JQH Arena and were members of the Missouri Valley Conference.

They advanced to the semifinals of the Missouri Valley Tournament where they lost to Northern Iowa.

They lost in the semifinals of the Missouri Valley Tournament to Evansville.

They received an automatic bid to the Women's National Invitation Tournament where they lost to Iowa in the first round.