They were eliminated from playoff contention on September 23 with their loss to the Tampa Bay Rays, 7+1⁄2 behind the Minnesota Twins for the 2nd AL Wild Card spot.
November 4: LF Joey Rickard & LHP Chris Lee activated from the 60-day disabled list.
November 30: New York Mets traded RHP Logan Verrett to Baltimore Orioles for cash.
December 2: RHP Vance Worley elected free agency; Baltimore Orioles claimed OF Adam Walker off waivers from Milwaukee Brewers.
January 6: Seattle Mariners traded RF Seth Smith to Baltimore Orioles for RHP Yovani Gallardo & cash.
January 20: Baltimore Orioles signed free agent RF Mark Trumbo.
February 19: Los Angeles Dodgers traded LHP Vidal Nuño to Baltimore Orioles for RHP Ryan Moseley.
February 21: New York Yankees traded LHP Richard Bleier to Baltimore Orioles for Player To Be Named Later.
February 25: Atlanta Braves claimed 1B Christian Walker off waivers from Baltimore Orioles.
March 13: Baltimore Orioles signed free agent DH Pedro Alvarez to a minor league contract & invited him to spring training.
March 31: Baltimore Orioles signed free agent 1B Ryan Ripken to a minor league contract.
April 2: RF Aneury Tavarez returned to Boston Red Sox from Baltimore Orioles.
April 7: Colorado Rockies traded RHP Miguel Castro to Baltimore Orioles for a player to be named later.
April 10: Baltimore Orioles traded RHP Joe Gunkel to Los Angeles Dodgers for a player to be named later.
May 2: Contract of C Francisco Pena selected from Norfolk Tides; RHP Damien Magnifico designated for assignment.
May 20: Chicago White Sox traded LHP Alex Katz to Baltimore Orioles for future considerations.
May 23: C Francisco Pena sent outright to AAA Norfolk; Baltimore Orioles released OF Michael Bourne from minor league contract.
May 24: Baltimore Orioles claimed SS Luis Sardinas off waivers from San Diego Padres.
June 4: LHP Paul Fry sent outright to AAA Norfolk; New York Yankees traded SS Ruben Tejada to Baltimore Orioles for cash.
June 10: C Francisco Pena designated for assignment; Baltimore Orioles signed LF Adam Brett Walker.
June 13: C Francisco Pena sent outright to AAA Norfolk; RHP Edwin Jackson elected free agency.
July 6: 1B David Washington designated for assignment; Contract of 2B Johnny Giavotella selected from AAA Norfolk.
July 8: SS Paul Janish designated for assignment; Milwaukee Brewers traded RHP Aaron Myers to Baltimore Orioles for future considerations.
July 29: Philadelphia Phillies traded RHP Jeremy Hellickson and cash to Baltimore Orioles for LF Hyun Soo Kim, LHP Garrett Cleavinger and future considerations.
August 5: Texas Rangers traded 2B Brallan Perez to Baltimore Orioles for future considerations.
September 17: RHP Richard Rodriguez sent outright to AAA Norfolk and designated for assignment; Contract of LHP Tanner Scott selected from AA Bowie.
September 1: LF Joey Rickard and RHP Jimmy Yacabonis recalled from AAA Norfolk.
September 2: LHP Donnie Hart and RHP Alec Asher recalled from AAA Norfolk.
April 2: LHP Wade Miley (Upper respiratory infection), RHP Chris Tillman (Right shoulder bursitis), & OF Anthony Santander (Strained right forearm) placed on the 10-day disabled list, retroactive to March 30.
August 17: SS Ryan Flaherty and OF Anthony Santander activated from the 60-day disabled list.