Just four days after the end of the regular season, the Astros met the Red Sox at home in the American League Division Series (ALDS), and defeated them in four games.

Combined with their NL pennant in 2005, the Astros became the first MLB team to make it to the World Series as members of both the National and American Leagues.

The Astros sent six players to the 88th All-Star Game held at Marlins Park in Miami, including Altuve, Springer, shortstop Carlos Correa, and pitchers Dallas Keuchel, Lance McCullers Jr., and Chris Devenski.

Bagwell, a first baseman who spent his entire 15-year major league career in an Astros uniform, was inducted into the Baseball Hall of Fame on July 30, 2017.

One of the most memorable and debated manifestations to hallmark the 2017 season was Jose Altuve's height and style of play contrasts with that of New York Yankees right fielder Aaron Judge.

At 6 feet 7 inches (2.01 m) and 280 pounds (130 kg), Judge was a rookie who emerged as his chief rival in the 2017 American League (AL) Most Valuable Player (MVP) race,[5] eventually breaking the record for both home runs hit (52) and walks drawn (127) by a rookie while leading the AL.[6] In July, a photo emerged of the pair standing side by side in game versus the Yankees that displayed their drastic size difference and became a viral phenomenon.

In that same span, McCullers also became the first Astros pitcher since Nolan Ryan in 1984 to allow no earned runs over at least five innings pitched in each of four consecutive appearances.

[8] During the May 14 game versus New York at Yankee Stadium, third baseman Alex Bregman hit his first major league grand slam off Masahiro Tanaka in a 10–7 Astros win.

His batting average and RBI total led the AL, on-base percentage ranked third, hits and OPS fifth, and slugging tied for sixth.

[11] In the July 9 game versus the Toronto Blue Jays, the Astros won 19–1 as Correa homered twice, collected four hits, and drove in a career-best five runs.

[14] For the first time in franchise history, three Astros players were elected by fans as starters for the All-Star Game, held at Marlins Park in Miami.

[13] Rookie third baseman Colin Moran sustained fractures of the facial bones during a game versus the Baltimore Orioles on July 22.

[13] On August 13, 2017, the Chicago White Sox traded reliever Tyler Clippard to the Astros for a player to be named later or cash considerations.

The games versus the Rangers were relocated to Tropicana Field in St. Petersburg, Florida, as more than 50 inches of rain inundated parts of Greater Houston and flooded more than one-third.

[22] Having lost 17 of 27 games as of August 31, the Astros acquired right-handed ace and former Cy Young Award winner Justin Verlander from the Detroit Tigers just moments before the trade deadline.

[22] Verlander won all five regular season starts in an Astros uniform to help lead them to a 22–8 record over their final month and an overall registry of 101–61, clinching the AL West division title.

[25] Moran returned to the Astros on September 19, having completed a rehabilitation assignment at Class-A Quad Cities River Bandits.

[35] The Astros also defeated the Yankees 4−0 in Game 7, on October 21, 2017, allowing them to advance to the World Series for the second time in franchise history, and first as a member of the American League.

[41] Brad Peacock replaced McCullers, completing the final 3+2⁄3 innings with no hits allowed and four strikeouts to earn his first major league save.

They eventually led 12–9 in the ninth inning, but the Dodgers made their own comeback to tie the game at 12 with a home run from Puig and an RBI single from Chris Taylor.

In the bottom of the 10th, Alex Bregman singled to left field off Dodgers closer Kenley Jansen to score pinch runner Derek Fisher for the walk-off hit.

He hit five home runs, tying the World Series record shared by Reggie Jackson and Dodgers second baseman Chase Utley.

Springer was named the World Series Most Valuable Player (MVP), hitting 11 of 29 at bats and driving in seven as the Astros' leadoff hitter.

[44][45] As a side note, Springer was featured on a 2014 cover of Sports Illustrated magazine that heralded a World Series win for the Astros in 2017.

[48] Verlander made six appearances and five starts, being credited with a 4–1 record, and gaining a 2.21 ERA, .177 batting average against, eight walks, and 38 strikeouts in 36+2⁄3 innings.

The Athletic article heavily stressed that the illegal sign stealing was hardly exclusive to the Astros, but was in fact rampant across Major League Baseball.

[65][66] Popular baseball content creator “Jomboy Media” was also one of the first to bring this to public attention, adding that specific drumming sounds were used to relay to batters what pitches were expected to be thrown from opposing pitchers.

Emails reveal that Astros management asked their employees who were scouting upcoming opponents: “One thing in specific we are looking for is picking up signs coming out of the dugout, .

[67] On January 13, 2020, Major League Baseball handed down punishments for the Astros ballclub in reference to the sign stealing allegations.

[1] As a consequence of MLB's announcement, Luhnow and Hinch were promptly fired by Astros' owner Jim Crane the same day.