The 2017 Louisville Cardinals football team represented the University of Louisville in the sport of American football during the 2017 NCAA Division I FBS football season.

The Cardinals competed in the Atlantic Division of the Atlantic Coast Conference and were led by fourth-year head coach Bobby Petrino, who began his second stint at Louisville in 2014 after eight years away.

Home games were played at Papa John's Cardinal Stadium in Louisville, Kentucky.

[1] The Cardinals were in a three-way tie for third place in the Atlantic Division[citation needed] and were invited to the TaxSlayer Bowl, where they lost 31–27 to Mississippi State.

The Cardinals had four players selected in the 2018 NFL draft.