2018–19 Clemson Tigers women's basketball team

The Tigers were led by first year head coach Amanda Butler.

The Tigers, members of the Atlantic Coast Conference, played their home games at Littlejohn Coliseum.

They advanced to the quarterfinals of the ACC women's tournament where they lost to Louisville.

They received an at-large bid of the NCAA women's tournament, which was their first trip since 2002 where they defeated South Dakota in the first round before losing to Mississippi State in the second round.

During the off-season it was announced that Amanda Butler would be taking over as head coach for Audra Smith.