The 2018–19 Pyramids season was the 10th season in the football club's history and 2nd consecutive and 3rd overall season in the top flight of Egyptian football, the Egyptian Premier League, having been promoted from the Egyptian Second Division in 2017.

Supplier: Kappa Sponsors: Saudia, Swyp Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Win Draw Loss Source: Competitions Source: Soccerway Pyramids entered the competition from the round of 32 and were given a home tie against Tanta.

Starting from the round of 16, all matches were played on stadiums selected by the Egyptian Football Association.