The 2018 Jacksonville State Gamecocks football team represented Jacksonville State University as a member of the Ohio Valley Conference (OVC) during the 2018 NCAA Division I FCS football season.

Led by fifth-year head coach John Grass, the Gamecocks compiled an overall record of 9–4, with a mark of 7–1 conference play, winning the OVC title for the fifth consecutive season.

Jacksonville State received the OVC's automatic bid to the NCAA Division I Football Championship playoff marking the program's sixth straight trip to the FCS playoffs.

The team played home games at Burgess–Snow Field at JSU Stadium in Jacksonville, Alabama.

Autry– G Darius Anderson – G Defense Randy Robinson – DL Marlon Bridges – DB Specialists Cade Stinnett – K