[1] Incumbent Democratic Senator Bob Casey Jr. ran for re-election to a third term.

[2] Casey, who faced no primary opposition, defeated the Republican nominee, Lou Barletta,[3] Green Party nominee Neal Gale,[4] and Libertarian Party nominee Dale Kerns.

[5] Casey was the first senator to be elected to a third term from Pennsylvania since Arlen Specter in 1992, and the first Pennsylvania Democrat to be popularly elected to three terms in the Senate.

State senators State representatives Newspapers Individuals Individuals Dale Kerns ran unopposed for the Libertarian nomination and received the official nomination from the Pennsylvania Libertarian Party at the state convention on March 6, 2018.

Representatives Local and state officials Labor unions Organizations Organizations Governors State and local politicians Individuals Organizations with Jim Christiana with generic Democrat and Republican Casey won 11 of 18 congressional districts, including the 1st and 10th districts, which elected Republicans to the House.