The 2019–20 season was Unione Sportiva Lecce's first season back in Serie A since being relegated at the end of the 2010–11 Serie A season.

The club competed in Serie A and in the Coppa Italia, starting in the third round.

The season was coach Fabio Liverani's third in charge and second full season after being appointed in September 2017.

Last updated: 2 August 2020.

Source: Competitive matches Last updated: 2 August 2020Source: Competitions