[1][2][3][4] LSU began the year ranked sixth in the preseason AP Poll, and were projected to finish second in the SEC West behind Alabama.

The Tigers secured an undefeated regular season that included wins over top-ten-ranked teams Texas, Florida, Auburn, and Alabama.

1 in the final College Football Playoff rankings of the season, earning them a spot in the national semi-final game to be played at the Peach Bowl.

Owing to their dominant performance against a historically difficult schedule, several pundits have called the team one of the greatest in college football history.

[13][14] Joe Burrow, who completed 23 of 27 passes for 278 yards and five touchdowns in just over one half of play, was later named SEC Co-offensive Player of the Week (with Alabama's Tua Tagovailoa).

After forcing a Texas three-and-out to open the game, LSU scored on its first offensive possession via a 36-yard field goal by Cade York.

Texas was forced to punt on its next possession, and LSU scored another touchdown in the final minute of the half with a 21-yard pass from Burrow to Jefferson.

For its third non-conference game of the season, LSU returned home to play in-state FCS foe Northwestern State of the Southland Conference.

Northwestern State received the opening kickoff, and their first drive ended with a failed fourth-and-seven attempt from the LSU 35 yard line.

LSU's opening drive advanced to the Northwestern State eight yard line, but they settled for a 26-yard Cade York field goal.

LSU responded with their own touchdown drive to reclaim the lead early in the second quarter via a four-yard run from Clyde Edwards-Helaire.

[21] In the second half, LSU removed all doubt by scoring touchdowns on each of their first four possessions and holding Northwestern State scoreless for the remainder of the game.

[23] at Tiger Stadium, Baton Rouge, Louisiana After a bye week, LSU played its fourth and final non-conference game at home against Utah State of the Mountain West Conference.

On the next drive, a Burrow pass was tipped and intercepted by Utah State's Cameron Haney and returned to the LSU 7 yard line.

LSU turned the ball over on downs on their next drive, and Utah State once again kicked a field goal, this time from 47 yards out to bring the score to 7–6 at the end of the first quarter.

On Burrow's last drive of the game before being benched, he threw an eight-yard touchdown pass to Thaddeus Moss to make the score 42–6 early in the fourth quarter.

LSU received the opening kickoff and advanced to the Florida 26 yard-line, but Cade York's 44-yard field goal attempt was no good.

LSU's next drive started with a 57-yard run by Clyde Edwards-Helaire, and ended with a nine-yard touchdown pass from Joe Burrow to Ja'Marr Chase to open the scoring of the game.

Alabama quarterback Tua Tagovailoa, who was only 20 days removed from a minor ankle surgery, was making his return, and the battle between him and Joe Burrow was expected to play a major role in the Heisman Trophy race.

LSU responded with a seven-yard touchdown pass from Burrow to Jefferson, and then converted a 52-yard field goal after an Ole Miss interception to make the score 44–23 heading into the fourth quarter.

Early in the final quarter, Joe Burrow threw an interception, and Ole Miss scored on the next play with a 35-yard run by Plumlee.

Linebacker JaCoby Stevens, who had a career high three sacks and four tackles for loss, was named SEC Defensive Player of the Week.

Safety Maurice Hampton, who was making his first career start in place of the injured Grant Delpit, had six tackles and was named SEC Freshman of the Week.

Quarterback Joe Burrow, in his final home game as a Tiger, made a pregame introduction to great fanfare wearing a jersey with the name "Burreaux" on the back, paying tribute to the French heritage of the state and university.

In the second quarter, LSU scored with a four-yard touchdown run by Tyrion Davis-Price, and a 51-yard field goal by Cade York.

In the third quarter, LSU's Cade York converted a 50-yard field goal, and then Texas A&M scored their only points of the day with a one-yard run by Isaiah Spiller.

Late in the fourth quarter, the Tigers pinned the Aggies at their own 1-yard line with a punt, and then Neil Farrell Jr. sacked James Foster in the endzone for a safety to end the scoring on the day at 50–7.

In the final College Football Playoff rankings of the year, LSU moved from second to first, passing Ohio State, who had beaten Wisconsin in the Big Ten Championship Game, 34–21.

After a missed 46-yard field goal attempt by LSU's Cade York early in the fourth quarter, Oklahoma scored again with a one-yard touchdown run by T.J. Pledger.

In the third quarter, Clemson pulled within three with a three-yard touchdown run by Travis Etienne and a successful two-point conversion via a pass from Lawrence to Amari Rodgers.