The 2019 North Alabama Lions football team represented the University of North Alabama during the 2019 NCAA Division I FCS football season.

The Lions played their home games at Braly Municipal Stadium as a first-year member of the Big South Conference.

They finished the season 4–7, 3–4 in Big South play, however due to their transition to NCAA Division I, their official conference record is 0–0.

Due to their transition to NCAA Division I, North Alabama was not ranked.

[1] The Lions had one player selected to the preseason all-Big South team.