All Wild Card Series games were played at the home field of the higher seeded team.

Game 1 was a low-scoring affair as both teams were held scoreless through the first three innings by Matt Shoemaker and Blake Snell.

Facing elimination, the Blue Jays tasked Hyun-jin Ryu with keeping their season alive while the Rays turned to Tyler Glasnow to send them to the ALDS.

The Rays then knocked Ryu out of the game in the second after a Mike Zunino two run homer and a Hunter Renfroe grand slam put up a six spot in the inning.

2020 ALWC (2–0): Tampa Bay Rays beat Toronto Blue Jays This is the first postseason series between the Athletics and White Sox.

Evan Marshall came on in relief and gave up one run on a Ramón Laureano fielder's choice before closing out the inning.

Álex Colomé pitched a perfect ninth to close out the game and give the White Sox a 1-0 series lead.

The Athletics struck first in the bottom of the first when Nick Madrigal mishandled a Matt Olson grounder that allowed two runs to score in the first inning.

Liam Hendriks struck out the side in the ninth to end the game and seal a 2–1 series win for the Athletics.

Game 1, the first time the two teams had faced each other in the postseason, featured Zack Greinke for the Astros against Kenta Maeda for the Twins.

Maeda turned in a strong performance, only allowing two hits over five innings while striking out five; however, George Springer laced an RBI double off of Tyler Duffey in the seventh to tie the game.

Caleb Thielbar came on in relief and promptly gave up a 2-run single to Michael Brantley to pad the Astros' lead at 4-1.

Framber Valdez, who had taken over for Greinke in the fifth, would allow two singles in the ninth, but induced a double play to end the game and give the Astros a 1–0 lead in the series.

This was the Twins’ 17th straight postseason loss, setting a team record for major professional sports in North America.

The Astros bullpen would finish the series with 9+2⁄3 scoreless innings, giving up only three hits while striking out ten across the two games.

The first game matched the prime stars for both squads in Gerrit Cole and Shane Bieber, with the latter having won the pitching Triple Crown for the 2020 season.

The Yankees took an early lead when Aaron Judge hit a home run on the first pitch he saw from Bieber, who had allowed the leadoff hitter in DJ LeMahieu to get on base with a single.

The Indians countered with a run on a José Ramírez double that made it 3–1, but a Carlos Santana strike out culled the chance for more with runners on the corner.

He was the second pitcher to throw thirteen strikeouts with zero walks and the first since Tom Seaver did so in Game 1 of the 1973 National League Championship Series.

Gio Urshela, facing James Karinchak, hit a grand slam on a full count to take the lead.

[14] This was also Francisco Lindor's last game with the Cleveland Indians, as he was traded along with Carlos Carrasco to the New York Mets in the off-season.

Sportsnet, a property of Toronto Blue Jays owner Rogers Communications, broadcast games in Canada.