[2] The draw for the first stage was held on 17 December 2019, 20:30 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay.
If still tied, extra time was not played, and a penalty shoot-out was used to determine the winner (Regulations Article 2.4.2).
Tied 2–2 on aggregate, Vélez Sarsfield won on away goals and advanced to the second stage.
Tied 1–1 on aggregate, Sport Huancayo won on away goals and advanced to the second stage.
Tied 1–1 on aggregate, Unión La Calera won on away goals and advanced to the second stage.
Tied 2–2 on aggregate, Independiente won on away goals and advanced to the second stage.