Originally known as the 2020 Copa Paraguay, the competition was scheduled to start on 14 April 2020 and conclude in late 2020, with the winners qualifying for the 2021 Copa Sudamericana as well as the 2020 Supercopa Paraguay against the Primera División champions with better record in the aggregate table.
As a result, the berth to the 2021 Copa Sudamericana was passed to the best team in the Primera División season that failed to qualify for international competition.
[5] Olimpia won their first Copa Paraguay title, beating Sol de América on penalties after a 2–2 draw over 90 minutes in the final.
[7] The competition is played as a single-elimination tournament, with all teams directly qualifying for the first round, where they were drawn into 32 single-legged ties.
Ties in all rounds will be played as a single game, with a penalty shootout deciding the winner in case of a draw.