The season was a tumultuous one, as Barcelona's economic problems forced the departure of Messi and Griezmann, in addition to not being able to replace them with quality players.
Barcelona finished third in their Champions League group and failed to reach the knockout stages for the first time since 2003, when it competed in the UEFA Cup after a disastrous domestic campaign the previous season.
Furthermore, poor domestic form saw Barça drop as low as ninth in the league by late October, which triggered head coach Ronald Koeman's sacking.
He was replaced by a club legend Xavi, who managed to reverse the team's fortunes with new winter signings Ferran Torres and Pierre-Emerick Aubameyang.
The team's highlight of the season was the 4–0 thrashing of Real Madrid at the Bernabéu, which helped propel them to the second place in the standings, one they never relinquished for the rest of the campaign.
Coupled with several league stumbles in April and May, in addition to earlier defeats in the Supercopa de España and Copa del Rey, Barça ended up trophyless, never managing to catch up with runaway leaders Real Madrid.
Barça had informed Betis that they would exercise their option to bring back Emerson after his two-year long loan spell with the Verdiblancos.
[8] On 4 July, Barcelona and Wolverhampton Wanderers reached an agreement for the loan of Francisco Trincão for the rest of the season with an option to buy for €29 million.
[9] On 6 July, Barcelona and Leeds United reached an agreement for the transfer of Junior Firpo for a fee of €15 million.
[10] On 7 July, UD Almería triggered Sergio Akieme's buy option for €3.5 million, with Barcelona reserving a right to 10% of any future sale and a right to first refusal.
[11] On 9 July, Barcelona and SK Rapid Wien reached an agreement over the loan of Yusuf Demir, with Barça receiving an option to buy for €10 million.
[13] On 17 July, Monchu joined Granada CF on a free deal following the expiration of his contract, with Barça reserving a right to 50% of any future sale, and a right to first refusal with a buyback option.
Goals from Gerard Piqué, Sergi Roberto and a brace from Martin Braithwaite ensured victory in their first La Liga match of the season.
[24] Barça also announced the signing of Luuk de Jong from Sevilla on a season long loan with an option to buy.
Barça conceded early in the match, but a goal from Ronald Araújo in the last minute of the game levelled the score.
Memphis, Luuk de Jong and Ansu Fati were the goalscorers, with the latter making his return after a 10-month absence due to injury.
[32] On 14 October, Barcelona and midfielder Pedri reached an agreement to extend the player's contract for a further four seasons through to 2026 with a release clause of €1 billion.
Valencia took the lead early in the match, but goals from Fati, Memphis and Philippe Coutinho ensured victory for Barça.
[35] Later that day Barcelona announced that they had reached an agreement with Ansu Fati to extend the player's contract for a further five seasons through to 2027 with a release clause of €1 billion.
[36] On 24 October, Barcelona were defeated in El Clásico 2–1 at home, with David Alaba and Lucas Vázquez scoring for Real Madrid.
[39] On 28 October, Barcelona announced the dismissal of Ronald Koeman as the first team coach, ending his spell at the club after 14 months.
Müller, Leroy Sané and Jamal Musiala scored for the home side, eliminating Barça from the group stage and making the Blaugrana play in the UEFA Europa League for the first time since 2003.
[56] On 21 December, Barcelona drew 1–1 with Sevilla at the Ramón Sánchez Pizjuán, with Papu Gómez opening the account for Los Rojiblancos and Araújo equalising in the dying moments of the first–half.
Luuk de Jong and Ansu Fati scored equalisers for Barça, but it was not enough as Madrid won 3–2 after extra time.
Atletico took an early lead but goals from Jordi Alba, Gavi, Araújo and Dani Alves provided a convincing victory for Barça.
[71] On 17 February, Barcelona opened their Europa league campaign with a 1–1 draw with Napoli at home in the first leg of the round of 32.
Aubameyang, Dembélé, Luuk de Jong and Memphis Depay scored for Barcelona to secure three points.
Elche scored late in the first half, but goals from Torres and Depay turned the game in favour of Barcelona.
[87] On 26 April, Barcelona and defender Ronald Araújo reached an agreement to extend the player's contract through to 2026 with a release clause of €1 billion.
[91] On 12 May, Aston Villa triggered Philippe Coutinho's option to buy for a fee of €20 million with Barça receiving a 50% sell-on percentage.