The 2021–22 Penn Quakers men's basketball team represented the University of Pennsylvania in the 2021–22 NCAA Division I men's basketball season.

The Quakers, led by sixth-year head coach Steve Donahue, played their home games at The Palestra in Philadelphia, Pennsylvania as members of the Ivy League.

Due to the COVID-19 pandemic, the Ivy League chose not to conduct a season in 2020–21.

[1][2] Roster Last update: October 30, 2021 Sources:[3][4]