The event returned to the Aldersley Leisure Village, Wolverhampton between 13–21 November 2021, after being held behind closed doors at the Ricoh Arena, Coventry in 2020.

José de Sousa was the defending champion, after defeating James Wade 16–12 in the 2020 final,[1] but he was eliminated in the second round, losing 10–9 to Peter Wright.

[4] She then went on to become the first woman to advance to the knockout stage, where she defeated Mensur Suljović in the second round, before losing to Peter Wright in the quarterfinals.

[3] On 11 November, it was announced that Dimitri Van den Bergh had tested positive for COVID-19, ruling him out of the tournament.

However, Gerwyn Price, who had already qualified, won both European Tour events, and thus this list produced no new competitors.

[8] Gerwyn Price (1) Peter Wright (2) Michael van Gerwen (3) James Wade (4) Chris Dobey (Alt)[a] Gary Anderson (6) José de Sousa (7) Jonny Clayton (8) Michael Smith Rob Cross Krzysztof Ratajski Joe Cullen Stephen Bunting Mervyn King Gabriel Clemens Luke Humphries Mensur Suljović Ryan Joyce John Henderson Boris Krčmar Mike De Decker Martin Schindler Raymond van Barneveld Bradley Brooks Lisa Ashton Rowby-John Rodriguez Jim Williams Matt Campbell Joe Davis Nathan Rafferty Fallon Sherrock Rusty-Jake Rodriguez [b] All group matches are best of nine legs After three games, the top two in each group qualify for the knock-out stage NB: P = Played; W = Won; L = Lost; LF = Legs for; LA = Legs against; +/− = Plus/minus record, in relation to legs; Pts = Points; Status = Qualified to knockout stage 13 November 14 November 15 November